Head Coach: Mark Dantonio (4th season)
Stadium: Spartan Stadium, East Lansing, MI
Record: 11-2 (7-1 Big Ten)
Previous: 2009
Next: 2011
Schedule/Results[]
| Date | Opponent | Result | Score | Record |
|---|---|---|---|---|
| 9/4 | Western Michigan | W | 38-14 | 1-0 |
| 9/11 | Florida Atlantic (1) | W | 30-17 | 2-0 |
| 9/18 | Notre Dame | W | 34-31 (OT) | 3-0 |
| 9/25 | Northern Colorado | W | 45-7 | 4-0 |
| 10/2 | Wisconsin | W | 34-24 | 5-0 (1-0) |
| 10/9 | @ Michigan | W | 34-17 | 6-0 (2-0) |
| 10/16 | Illinois | W | 26-6 | 7-0 (3-0) |
| 10/23 | @ Northwestern | W | 35-27 | 8-0 (4-0) |
| 10/30 | @ Iowa | L | 6-37 | 8-1 (4-1) |
| 11/6 | Minnesota | W | 31-8 | 9-1 (5-1) |
| 11/20 | Purdue | W | 35-31 | 10-1 (6-1) |
| 11/27 | @ Penn State | W | 28-22 | 11-1 (7-1) |
| Capital One Bowl (@ Citrus Bowl, Orlando, FL) | ||||
| 1/1 | Alabama | L | 7-49 | 11-2 (7-1) |
- (1) - @ Ford Field, Detroit, MI